武警医学2012，Vol.23Issue(8)：662-663,667,3.
氟骨症与强直性脊柱炎临床特点对照分析
Analysis of clinical features of 62 cases of skeletal fluorosis of and a comparison with 54 cases of ankylosing spondylitis
王岚 1赵扬辉 1苏静 1田媛媛 1张懿芳 1李霞 1张莉芸2
作者信息
- 1. 030006,太原,武警山西总队医院风湿免疫科
- 2. 030006,太原,山西大医院风湿免疫科
- 折叠
摘要
Abstract
Objective To explore the differential diagnosis between skeletal fluorosis and ankylosing spondylitis. Methods 62 patients of skeletal fluorosis provided by a specialized hospital in Shanxi province and 54 AS patients admitted to Shanxi Provincial Corps Hospital from August 2009 to March 2010 were retrospectively analyzed. Results The age of onset(42. 9 ?6. 66) and number of peripheral joint pain (≤3) in skeletal fluorosis group were above those in AS group, and the difference was statistically significant (P<0.01). The rate of deterioration after exercise( 83.9% ,52 cases) was higher than that in AS group ( 5.56% , 3 cases) (P < 0.01). The positive rate of HLA - B27 in skeletal fluorosis group (3.2% , 2 cases) was lower than that in AS group( 90.7% ,49 cases) (P <0. 01) . The rate of limb bone lesions ( 100% , 62 cases) , peripheral joint disease(90. 3% , 56cases) and interosseous membrane calcification(27.4% , 17 cases) was higher than in AS group(P <0. 01) . The rate of spinal slub amyloidosis(61. 3% , 38 cases) was higher than that in AS group (22. 2% , 12cases) (P <0. 05) . The rate of bone destruction in skeletal fluorosis group(0% , 0 cases) was lower than that in AS group(29.6% ,16 cases) (P<0.01). Conclusions Correct diagnosis should be made based on epidemiology -^clinical manifestations、HLA —1527 test and imaging manifestations between skeletal fluorosis and ankylosing spondylitis.关键词
氟骨症/强直性脊柱炎/鉴别诊断Key words
skeletal fluorosis/ankylosing spondylitis/differential diagnosis分类
医药卫生引用本文复制引用
王岚,赵扬辉,苏静,田媛媛,张懿芳,李霞,张莉芸..氟骨症与强直性脊柱炎临床特点对照分析[J].武警医学,2012,23(8):662-663,667,3.
