武警医学2012,Vol.23Issue(8):682-685,4.
雌、孕激素受体蛋白在子宫肉瘤中的表达及其相关性研究
Study on the expression of estrogen receptors and progesterone receptors in uterine sarcoma and their correlation
闫大晶 1王宏宾 1吴倩 1王敏2
作者信息
- 1. 110034,沈阳,武警辽宁总队医院妇产科
- 2. 110004,沈阳,中国医科大学附属盛京医院妇产科
- 折叠
摘要
Abstract
Objective To examine the expression & correlation of estrogen receptors, progesterone receptors in uterine sarco-
coma. Their correlation was analyzed. Results There was significant difference in the positive rate of ERa protein between endometri-al stromal sarcoma tissues, uterine leiomyosarcoma tissues and uterine care i no sarcoma tissues(P <0. 01) on one hand and normal myo-metrium tissues on the other hand. The PRA-, PRB positive rate of endometrial stromal sarcoma tissues was considerably different (P < 0. 05) from that of uterine leiomyosarcoma tissues and uterine carcinosarcoma tissues. Conclusion ERa, ERp and PRA, PRB were
all expressed in endometrial stromal sarcoma tissues,uterine leiomyosarcoma tissues,yterine carcinosarcoma tissues,and normal myo-
metrium tissues. The expression of ERa is positively correlated with PRA and PRB in endometrial stromal sarcoma tissues.关键词
ERa/ERβ/PRA/PRB/免疫组织化学染色/子宫肉瘤Key words
estrogen receptor a/ estrogen receptor p/ progesterone receptor A/ progesterone receptor B/ immunohistochemis-try/ uterine sarcoma
分类
医药卫生引用本文复制引用
闫大晶,王宏宾,吴倩,王敏..雌、孕激素受体蛋白在子宫肉瘤中的表达及其相关性研究[J].武警医学,2012,23(8):682-685,4.