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雌、孕激素受体蛋白在子宫肉瘤中的表达及其相关性研究

闫大晶 王宏宾 吴倩 王敏

武警医学2012,Vol.23Issue(8):682-685,4.
武警医学2012,Vol.23Issue(8):682-685,4.

雌、孕激素受体蛋白在子宫肉瘤中的表达及其相关性研究

Study on the expression of estrogen receptors and progesterone receptors in uterine sarcoma and their correlation

闫大晶 1王宏宾 1吴倩 1王敏2

作者信息

  • 1. 110034,沈阳,武警辽宁总队医院妇产科
  • 2. 110004,沈阳,中国医科大学附属盛京医院妇产科
  • 折叠

摘要

Abstract

Objective To examine the expression & correlation of estrogen receptors, progesterone receptors in uterine sarco- coma. Their correlation was analyzed. Results There was significant difference in the positive rate of ERa protein between endometri-al stromal sarcoma tissues, uterine leiomyosarcoma tissues and uterine care i no sarcoma tissues(P <0. 01) on one hand and normal myo-metrium tissues on the other hand. The PRA-, PRB positive rate of endometrial stromal sarcoma tissues was considerably different (P < 0. 05) from that of uterine leiomyosarcoma tissues and uterine carcinosarcoma tissues. Conclusion ERa, ERp and PRA, PRB were all expressed in endometrial stromal sarcoma tissues,uterine leiomyosarcoma tissues,yterine carcinosarcoma tissues,and normal myo- metrium tissues. The expression of ERa is positively correlated with PRA and PRB in endometrial stromal sarcoma tissues.

关键词

ERa/ERβ/PRA/PRB/免疫组织化学染色/子宫肉瘤

Key words

estrogen receptor a/ estrogen receptor p/ progesterone receptor A/ progesterone receptor B/ immunohistochemis-try/ uterine sarcoma

分类

医药卫生

引用本文复制引用

闫大晶,王宏宾,吴倩,王敏..雌、孕激素受体蛋白在子宫肉瘤中的表达及其相关性研究[J].武警医学,2012,23(8):682-685,4.

武警医学

OACSTPCD

1004-3594

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