现代妇产科进展2012,Vol.21Issue(6):427-430,4.
IVF周期中MⅡ末期卵子形态与胚胎发育潜能的关系
Relationship between the telophase of M Ⅱ oocytes morphology and the embryonic development potential in IVF-ET
杨爱军 1王钦 1王雪楠 1牛焕付 1曹井贺 1陈晓丽1
作者信息
- 1. 济宁医学院附属医院生殖医学科,济宁272029
- 折叠
摘要
Abstract
Objective:To invesligate and analyse the relationship between the telophase of MⅡ oocytes morphology and the embryonic development potential in IVF-ET. Methods: Oocytes at telophase of M Ⅱ were evaluated with oocyte morphology based on the zona pellucida, follicular plasma, and the both polar bodys morphology with light microscope after granulosa cells removed, according to morphology, oocytes were divided into three groups (Ⅰ~Ⅲ ). Graded oocytes were compared with each other in pronucleus of high scored Z1/Z2 formation rale, cleavage rate,high quality embryo rale and clinical pregrancy rate respectively. Results; Morphological scoring egg from ⅠtoⅢgrade, the rates of fertilization and cleavage were not significantly different ( P > 0. 05 ). But the high quality embryo rates decreased significantly ( P < 0.05). Along with the increased of the numbers of transfered embryos which was development from high morphorlogy scored oocytes, clinical pregnancy rate, implantation rale increased (P< 0.05). Conclusion;In conventional IVF cycles,the telophase of MⅡ oocytes morphology have no effect on the high graded pronuclear formation and cleavage rate,but it may play an important role to indicate the potential of early embryonic development.关键词
体外受精/MⅡ末期/卵子形态/胚胎发育潜能Key words
In vitro fertilization/Telophase of M Ⅱ/Oocytes morphology/ Embryonic development potential分类
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杨爱军,王钦,王雪楠,牛焕付,曹井贺,陈晓丽..IVF周期中MⅡ末期卵子形态与胚胎发育潜能的关系[J].现代妇产科进展,2012,21(6):427-430,4.