新医学2012，Vol.43Issue(8)：559-562,4.DOI:10.3969/g.issn.0253-9802.2012.08.012
广州地区非洲籍群体17个Y-STR基因座遗传多态性及群体遗传分析
Genetic polymorphism of 17 Y-STR loci in Guangzhou African population and analysis of population genetic distance
摘要
Abstract
Objective: To investigate the genetic polymorphisms of 17 Y-ehromosomal short tandem repeatsau -thor (STR) loci in Guangdong African population , provide basic statistics data for forensic application and to analyze the genetic relationships with 4 other populations. Methods: Seventeen Y-STR loci ( DYS456, DYS389I, DYS390, DYS389 II, DYS458, DYS19, DYS393, DYS385a/b, DYS391, DYS439, DYS635, DYS392, GATA H4, DYS437, DYS438, DYS448) were detected from 104 unrelated Guangzhou African male individuals by AmFISTR Yfiler kit . We compared the above genetic information with Chinese Han population and three other Af -rican populations. Results: A total of 98 haplotypes were identified , 5 of which were found twice. The overall hap-lotype diversity for the 17 Y-STR loci was 0. 9991. Compaed with 4 other populations , the genetic distance between Guangzhou African population and Chinese Han population was the largest (0. 3576) , while that between Guangzhou African population and Namibia population was the smallest (0. 0512). Conclusion: Multiplex detection of the 17 Y-STR loci by AmFISTR Yfiler kit revealed a highly genetic polymorphsm. The Y-STR data investigated in this study would be useful in individual and fatherhood identification as well as population genetics analysis .关键词
Y染色体/短串联重复序列/群体/遗传多态性/遗传距离Key words
Y chromatosome/ STR/ population/ genetic polymorphism/ genetic distance引用本文复制引用
刘宏,刘超,刘长晖,汪冠三,马文丽..广州地区非洲籍群体17个Y-STR基因座遗传多态性及群体遗传分析[J].新医学,2012,43(8):559-562,4.基金项目
公安部应用创新计划资助项目(2011YYCXGDST076) （2011YYCXGDST076）
广东省科技计划项目(2010A060801001) （2010A060801001）
