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γ-谷氨酰转肽酶与血压的相关性分析

王小平 李利华 姚超永 李雪艳 董宵 朱学创 尹雪艳 吴新华

中国动脉硬化杂志2012,Vol.20Issue(9):802-804,3.
中国动脉硬化杂志2012,Vol.20Issue(9):802-804,3.

γ-谷氨酰转肽酶与血压的相关性分析

Correlation Between γ-glutamyl Transferase and Blood Pressure

王小平 1李利华 1姚超永 1李雪艳 1董宵 1朱学创 1尹雪艳 1吴新华1

作者信息

  • 1. 大理学院附属医院心内科,云南省大理市671000
  • 折叠

摘要

Abstract

Aim To explore the correlation between serum γ-glutamyl transferase (γ-GT) and blood pressure. Methods 1480 subjects were enrolled in the cross-sectional study, and standard questionnaire was used to collect information on smoking, alcohol intake and medication. Fasting blood was drawn to test γ-GT, serum glucose, liver and renal function, and body weight, body height and blood pressure were measured. Results 1480 subjects included 886 male and 594 female with age range from 20 to 84 years old. By Pearson correlation analyses, γ-GT was positively correlated with systolic blood pressure, diaslolic blood pressure, total cholesterol, serum glucose, low density lipoprotein cholesterol, serum uric acid, serum creatinine and body mass index, and negatively correlated with high density lipoprotein cholesterol. Compared with the lowest quartile, the highest quartiie had significantly higher level of systolic blood pressure, diastolic blood pressure, total cholesterol, serum glucose, alanine aminotransferase and aspartate aminotransferase. After adjustment of sex, age, body mass index, current smoking, current alcohol intake, Logistic regression analysis indicated that there was a 74% higher risk of hypertension when compared the highest quartile with the lowest quartile ( OR = 1. 74, 95<% CI was 1.13~2.68, P = 0.01). Conclusion γ-GT was positively correlated with blood pressure and can predict hypertension in Chinese.

关键词

γ-谷氨酰转肽酶/血压/高血压

Key words

γ-ghitamyl Transferase /Blood Pressure/ Hypertension

分类

医药卫生

引用本文复制引用

王小平,李利华,姚超永,李雪艳,董宵,朱学创,尹雪艳,吴新华..γ-谷氨酰转肽酶与血压的相关性分析[J].中国动脉硬化杂志,2012,20(9):802-804,3.

基金项目

国家自然科学基金(30960137) (30960137)

中国动脉硬化杂志

OA北大核心CSCDCSTPCD

1007-3949

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