局解手术学杂志2012，Vol.21Issue(4)：389-391,3.
多层羊膜填塞治疗微小角膜溃疡穿孔
Multilayer amniotic membrane plugging for the treatment of small corneal perforation associated with ulceration
周雄 1曾波1
作者信息
- 1. 解放军广州军区武汉总医院眼科医院,湖北,武汉,430070
- 折叠
摘要
Abstract
Objective To investigate the efficacy, safety and limitation of multilayer amniotic membrane plugging for small corneal perforation associated with ulceration. Methods 12 cases ( 12 eyes ) of small corneal perforation secondary to ulceration were treated by amniotic membrane plugging including 6 cases of bacterial keratitis,2 cases of virus keratitis and 4 cases of fungal keratitis. The size of the perforation was 0. 5 ~ 3. 0 mm in diameter. The necrotic tissues were removed and the multilayer amniotic membrane was applied to tamp the perforation and another big amniotic membrane was covered on the surface of the entire cornea. Postoperative medication was continued to treat the original diseases. All patients were followed up for 6～24 months and the reformation of the anterior chamber,recovery of the ulcer,corneal thickness and complications were observed. Results The anterior chamber was reformed at the first day postoperatively and was kept in normal depth in the follow-up time with perforation area being closed tightly. Between postoperative 40 ~ 60 days, the ulcer was recovered with scar and the surface of the ulcer was covered with corneal epithelium, whose thickness was normal. The vision of all patients was improved with different degrees. During the follow-up, no case of recurrence or severe complication was noticed. Conclusion Multilayer amniotic membrane plugging is safe and effective in the treatment of small corneal perforation associated with ulceration, but the ulcer was healed with scar.关键词
羊膜填塞/角膜溃疡穿孔/瘢痕愈合Key words
amniotic membrane plugging/corneal perforation associated with ulceration/ scar recovery分类
医药卫生引用本文复制引用
周雄,曾波..多层羊膜填塞治疗微小角膜溃疡穿孔[J].局解手术学杂志,2012,21(4):389-391,3.
