中国康复2012，Vol.27Issue(3)：227-228,2.DOI:10.3870/zgkf.2012.03.028
重复经颅磁刺激对慢性精神分裂症阴性症状的疗效
Effectiveness of repetitive transcranial magnetic stimulation on negative symptoms of patients with chronic schizophrenia
吴越 1季萍 1汤莉 1杨国平1
作者信息
- 1. 无锡市精神卫生中心老年精神科,江苏无锡214151
- 折叠
摘要
Abstract
Objective! To observe the effect and safety of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms of patients with chronic schizophrenia. Methods: 48 patients with chronic schizophrenia were randomly divided into real rTMS group (study group) and sham rTMS group (control group). with 24 cases in every group. Study group received real rTMS sessions over 4 weeks to the left dorsolateral prefrontal cortex, while the control group received sham rTMS treatment. All patients were given anti-psychotic drug treatment. Both groups were assessed by using Positive and Negative Syndromes Scale (PANSS), and scale for the Assessment of Negative Symptoms (SANS). Results! There were no severe adverse events in the treatment. After 4 weeks of treatment, scores of PANSS and SANS scales in study group were significantly lower than those before treatment and those in control group (P<0. 05). Conclusion: Combination of rTMS and antipsychotics is an effective method in treating negative symptoms of patients with chronic schizophrenia.关键词
重复经颅磁刺激/精神分裂症/阴性症状Key words
repetitive transcranial magnetic stimulation) schizophrenia) negative symptom分类
医药卫生引用本文复制引用
吴越,季萍,汤莉,杨国平..重复经颅磁刺激对慢性精神分裂症阴性症状的疗效[J].中国康复,2012,27(3):227-228,2.
