摘要
Abstract
AIM: To observe the therapeutic effect of HFMD combine with encephalitis by monosialoteterahexosyl ganglioside ( GM-1 ), METHODS: 139 cases in our hospital from April 2010 to November 2010 were randomly divided into two groups, one with 81 cases as a treatment group and another with 58 cases as control group. All of the two groups were accepted the treatment of GG + MePr + MNT + FSM i. v. within antiviral therapy. The treatment group was added ivgtt of the 5%GS 50 mL with GM-1 20 mg , 10-14 days as one course of treatment. RESULTS:The times of Symptoms improved after treatment, including muscle tension, startle, lethargy, vomiting of treatment group were (8. 0 ±3. 2), (4. 2±1.0),(3. 6±1. 3),(2. 8±0. 8) d.
control group were (10. 3 ± 3. 8), (4. 8 ± 1. 3), (4. 2± 1.3), (3. 2+1.0) d, each indicator had statistically significant difference (P<0. 05). In treatment group, excellence 43 cases, utility 29 cases, ineffective 9 cases, the total effective rate was 88. 89%. In control group, excellence 21 cases, utility 22 cases, ineffective 15 cases,the total efficiency rate was 74. 14%. The trerapeutic effect of treatment group was better than that of control group (P<0. 05). CONCLUSION: GM-1 can rapidly relieve the clinical symptoms, improve the recovery rate, and has no significant adverse reactions, is safe and effective.关键词
单唾液酸四己糖神经节苷脂/手足口病/脑炎Key words
GM-1/HFMD/Encephalitis分类
医药卫生
