中国临床药理学与治疗学2012，Vol.17Issue(4)：445-447,3.
甲氨蝶呤联合米非司酮治疗输卵管妊娠疗效观察
Curative effect of MTX combined with mifepristone in the treatment of tubal pregnancy
丁华峰 1何莲芝 1施素华1
作者信息
- 1. 皖南医学院附属弋矶山医院妇产科,芜湖241000,安徽
- 折叠
摘要
Abstract
AIM: To observe the effectiveness of methotrexate combined with mifepristone for tubal pregnancy treatment. METHODS: A total of 98 cases of ectopic pregnancy were diagnosed as unrupture tubal pregnancy that be randomly divided into two groups from Jan. 2008 to Jun. 2010, each group 49 cases. Study group was treated with MTX single-dose (50 mg/nr ) intramuscular injection combined with mifepristone. Control group was treated with MTX single-dose (50 mg/m2) intramuscular injection only . After treatment, the curative effect and adverse effect between the two groups were compared. RESULTS: The rate of tubal pregnancy package of block reduction and the serum|3-HCG descent exceeded 30% in study group. Less time
of average hospitalization in study group significantly differed from the control group (P < 0.05). And the lateral oviduct recanalization rate of the study group was 75. 0% (24/32 ), which was higher than that of the control group 64. 3% (18/28). CONCLUSION; The combination of single-dose MTX intramuscular injection with mifepristone in treating tubal pregnancy is effective and has minor side effect. The procreation function is reserved and it is acceptable for patients.关键词
甲氨蝶呤/米非司酮/输卵管妊娠Key words
Methotrexate/ Mifepristone/Tubal pregnancy分类
医药卫生引用本文复制引用
丁华峰,何莲芝,施素华..甲氨蝶呤联合米非司酮治疗输卵管妊娠疗效观察[J].中国临床药理学与治疗学,2012,17(4):445-447,3.
