中国全科医学2012，Vol.15Issue(19)：2228-2231,4.DOI:10.3969/j.issn.1007-9572.2012.07.030
极低和超低出生体质量儿医院感染的十年变迁
Change of Nosocomial Infection of Very Low or Extremely Low Birth Weight Infants in the Last 10 Years
吴俊 1吴本清 1黄进洁 1罗亮 1陈霆1
作者信息
- 1. 518020广东省深圳市人民医院新生儿科,暨南大学第二临床医学院
- 折叠
摘要
Abstract
To investigate the change trends of pathogens and epidemiological condition of nosocomial infection ( NI ) of very low or extremely low birth weight infants in neonate intensive care unit ( NICU ) . Methods The data of 654 very low or extremely low birth weight infants in NICU of our hospital from January 2001 to December 2010 were investigated retrospectively. The 162 infants diagnosed with nosocomial infection were divided into 2 groups according to their hospitalization periods ; from 2001 to 2005 ( group I ) and from 2006 to 2010 ( group H )The NI rate, infected site and pathogens were comparatively analyzed between the two groups. Results The NI rate was 22. 55% in group I and 26. 01% in group H , with no statistical difference (P>0.05). The most common infection was pneumonia, and the proportion of pneumonia in the late 5 years decreased, but with no statistical difference ( P>0.05). However the proportion of sepsis increased from 22. 6% to 38. 5% ( P<0.05). The major pathogens of NI were gram - negative bacteria in the two groups, and the proportion of gram - positive bacteria and fungus had increased, Klebsiella pneumoniae became the forst pathogen to cause NI, and coagulase negative staphylococcus increased significantly ( P <0.05) . Conclusion The NI rate in very low or extremely low birth weight infants presents an as-
cending Trend,and the consTituent raxioof sepsis inci eases. So xne amirnoTics snouin oe laxionan y chosen ac cordining to the change
of pathogenic spectrum.关键词
医院感染/极低出生体质量儿/超低出生体质量儿/病原菌Key words
Nosocomial infection/Very low birth weight infants/ Extremely low birth weight infrant/Pathogens分类
医药卫生引用本文复制引用
吴俊,吴本清,黄进洁,罗亮,陈霆..极低和超低出生体质量儿医院感染的十年变迁[J].中国全科医学,2012,15(19):2228-2231,4.
