中国全科医学2012，Vol.15Issue(21)：2484-2486,3.DOI:10.3969/j.issn.1007-9572.2012.07.123
β-七叶皂苷钠联合甘露醇治疗重型颅脑损伤的疗效观察
Clinical Study on the Efficacy of β-Aescine Sodium Combined with Mannitol in the Treatment of Severe Brain Injury
摘要
Abstract
To study the clinical efficacy of p - aescine sodium combined with mannitol in the treatment of severe brain injury. Methods 60 patients with severe brain injury admitted to our hospital from June 2009 to June 2011 were randomly divided into treatment group ( 30 cases ) and control group ( 30 cases ) . The control group was routinely given 20% mannitol, neurotrophic and anti - infection treatment. While the treatment group was given β - aescine sodium in addition to reduce in-tracranial pressure ( ICP ) . The ICP before the treatment and Glasgow Coma Scale ( GCS ) before and after the treatment of the two groups were compared. Glasgow Outcome Scale ( GOS ) was conducted three and six months after treatment respectively. Results The ICP and GCS in the treatment group showed statistically significant differences compared with control group after-treatment ( P<0. 05) . The three - month and six - month after treatment showed that the difference of GOS between treatment group and control group was also statistically significant ( P < 0.05 ) . Conclusion The efficacy of β - aescine sodium combined with mannitol in the treatment of severe brain injury is satisfactory, can significant reduce the intracranial pressure, and improve the results of short - term GCS and long - term GOS.关键词
β-七叶皂苷钠/甘露醇/颅脑损伤/治疗结果Key words
β- aescine sodium/ Mannitol/ Craniocerebral trauma/ Treatment outcome分类
医药卫生引用本文复制引用
邓元央,黄海能,韦桂源,黄华东,罗起胜,符黄德,李传玉..β-七叶皂苷钠联合甘露醇治疗重型颅脑损伤的疗效观察[J].中国全科医学,2012,15(21):2484-2486,3.基金项目
广西卫生厅科研立项课题(Z2010088) （Z2010088）
