Abstract
Objective To study the significance of serum albumin (ALB), retinol-binding protein (KBP), prealbumin (PA) ,fibronectin (FN), transferrin (TRF) ,leptin (LP) and amino acids in malnourished children, to detect sensitive indicators of the effectiveness of enteral nutrition. Methods 30 outpatients from health care clinic from January to Februry 2010 and 30 malnourished inpatients from February 2009 to Februry 2010 were chosen in Department of Gastro-enterology, Women and Children' s Medical center. Routine blood test and serum ALB, TRF, PA, RBP,FN,LP,TC, ami-no acid were determined respectively before continued nasogastric feeding and 10 days later. Results Serum RBP,PA, FN,TRF,LP were significantly higher than before (P< 0.01 or P < 0.05) ,no change was observed in height, weight, BMI, TSF, MAC, MAMC, TC, Hb, RBC, MCHC, TLC, ALB (P > 0.05). There were significant positive correlations between BMI and ALB, RBP,PA, FN,TRF; ALB and RBP,PA, FN,TRF;PA and BMI,ALB,RBP,FN,TRF,LP;LP and BMI, ALB, RBP, PA. Glutamine, histidine, isoleucine, alanine, valine, arginine, leucine, lysine, EAA, EAA/NEAA, BCAA were significantly higher than before (P< 0.01 or P< 0.05),tyrosine,phenylalanine and total aromatic amino acids decreased significantly (P< 0.01 or P< 0.05). Conclusion RBP,PA,FN,TRF,LP and amino acids were sensitive indicators to assess the effectiveness of enteral nutrition.关键词
血清白蛋白/视黄醇结合蛋白/前白蛋白/纤维连接蛋白/转铁蛋白/瘦素/血氨基酸谱/肠内营养Key words
albumin/retinol-binding protein/ prealbumin/fibronectin/ transferrin/ leptin/amino acids/enteral nutrition分类
医药卫生
