摘要
Abstract
Objective To analyze lhe function of the peri-operalive cell immune system in elderly e-sophageal cancer patients underwent thoracoscopic and laparoscopic surgery. Methods The clinical data was retrospectively analyzed in 66 cases of elderly esophageal cancer patients. The patients were divided into lwo groups, conventional surgery group (T group) underwent lhe traditional open surgery, laparoscopic surgery with video-assisted thoracoscopy group (V group) underwent the combined endoscopic surgery. And lhe peri-operative cell immune functions were checked for all patients. Results Compared with the T group, the duration of the operation time, the length of the incision, the postoperative pain scores, the a-mount of bleeding and the hospitalization time were all less in the V group (P < 0. 01 ). And in the T group, CD4 + , CD4 + /CD8 + and NK cells significantly decreased 7 days after operation (P <0.01 ) , and CD4 + was lower than thai of the V group (P < 0.05). While in lhe V group, only CD4 + decreased (P < 0.01) and the other data was not changed significantly. Conclusion Compared with the traditional operation, the combined endoscopic operation is less trauma, less bleeding, more rapid recovery, and less impact on the peri-operative cell immune functions.
关键词
食管肿瘤/胸腔镜检查/腹腔镜检查/CD4阳性T淋巴细胞/CD8阳性T淋巴细胞/杀伤细胞,天然Key words
esophageal neoplasms/ thoracoscopy/ laparoscopy/ CD4-positive T-lymphocytes/ CD8-posilive T-lymphocytes/ killer cells, natural
分类
医药卫生
