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低分子肝素钙在脾切断流术后预防门静脉血栓形成的临床观察

杨健 钟麟

中国药房2012,Vol.23Issue(24):2254-2257,4.
中国药房2012,Vol.23Issue(24):2254-2257,4.DOI:10.6039/j.issn.1001-0408.2012.24.19

低分子肝素钙在脾切断流术后预防门静脉血栓形成的临床观察

Clinical Observation of Low-molecular Heparin Preventing Pylethrombosis after Peri-esophagogastric Devascularization and Splenectomy

杨健 1钟麟2

作者信息

  • 1. 大连大学附属中山医院物管中心,辽宁大连116001
  • 2. 大连大学附属中山医院肾内科,辽宁大连116001
  • 折叠

摘要

Abstract

OBJECTIVE: To observe the effects of low-molecular heparin preventing pylethrombosis after peri-esophagogastric devascularization with splenectomy. METHODS: 100 patients with portal hypertension in our hospital during 2010—2011 were randomly divided into treatment group(48 cases) and control group(52 cases). The control group was given conventional treatment while the treatment group was given low-molecular heparin to prevent thrombosis prospectively. Clinical information of patients and the incidence of post-operative thrombosis were compared between 2 groups. RESULTS: The blood flow velocity of portal vein had significant difference between 2 groups (P<0.05). There was significant difference in the incidence of pylethrombosis between 2 groups within 1 month after operation (P<0.05). CONCLUSION: Low-molecular heparin can prevent the formation of pylethrombosis effectively. Moreover, it is worthy of spreading because of simple medication method, no call for local special care, and easy to use.

关键词

门静脉高压症/脾切断流术/门静脉血栓形成/低分子肝素钙

Key words

Portal hypertension/ Splenectomy/ Pylethrombosis/ Low-molecular heparin

分类

医药卫生

引用本文复制引用

杨健,钟麟..低分子肝素钙在脾切断流术后预防门静脉血栓形成的临床观察[J].中国药房,2012,23(24):2254-2257,4.

中国药房

OACSCDCSTPCD

1001-0408

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