中国药理学通报2012，Vol.28Issue(9)：1224-1228,5.DOI:10.3969/j.issn.1001-1978.2012.09.010
红景天中8种成分体外抗氧化作用的比较
Comparison on the antioxidant activity of eight components from Rhodiola in vitro
摘要
Abstract
Aim To make a comparative study of the antioxidant activity of eight kinds of glycosides or alcohols from Rhodiola in vitro, including Rutin, Salidro-side, Isoquercitrin, Tyrosol, Rosarin, Brbutin, Rosa-vin, Cinnamyl alcohol. Methods The antioxidant activities were evaluated by total anti-oxidative capacity assay, antilipid peroxidation capacity assay, 1,1 -di-phenyl-2-picrylhydrazyl ( DPPH ) free radical scavenging activity assay, superoxide anion scavenging activity assay, NO free radical scavenging activity assay and hydroxyl scavenging activity assay. Results Isoquercitrin and Rutin showed significantly stronger antioxidant activity than other components in all assays except hydroxyl scavenging. In DPPH radical scavenging, superoxide anion radical scavenging, antilipid peroxidation assays, IC50 value were 5. 72 and 10. 46, 23. 63 and 36. 39, 10. 78 and 56. 49 mg · L-1 respectively. While Tyrosol and Salidroside showed stronger antioxidant activity in hydroxyl scavenging, their IC50 were 10. 84 and 18. 97 mg · L-1. Conclusions Glycosides or alcohols from Rhodiola have scavenging activities on various of free radicals and have excellent antioxidation property and a prospective future of applications.关键词
红景天/抗氧化/自由基/苷类/醇类/体外/比较Key words
Rhodiola/ antioxidant/ free radical/ glycosides / alcohols/ in vitro/ comparison分类
医药卫生引用本文复制引用
马天翔,史宁,陈乾,郭洪举,吴久鸿..红景天中8种成分体外抗氧化作用的比较[J].中国药理学通报,2012,28(9):1224-1228,5.基金项目
国家自然科学基金资助项目(No 30772631) （No 30772631）
