摘要
Abstract
Objective To establish the quality standard for Xincangbishu Capsules. Methods The qualitative identification of Rhizoma Chuanxiong, Fructus Xanthii and Flos Magnoliae in Xincangbishu Capsules were carried out by TLC. The content of α-pinene,β-pinene and cineole in the preparation were determined at the same time by the capillary gas chromatography with sequential increase of temperature programming. The capillary column DB-l(30 m × 0. 25 mm, 0. 25 μm) was used with the injector temperature of 230 ℃ , the flame ionization detector (FID) temperature of 250 ℃. Results The relevant spots of Rhizoma Chuanxiong, Fructus Xanthii and Flos Magnoliae on TLC plates were clear without the interference of the negative control. The good linearity relationship of α - pinene was during the range of 0.008-0.091 g/L(r= 0.999 8), the average recovery rate was 92.09% with RSD of 1.23% (n=5);the good linearity relationship of β - pinene was during the range of 0.009-0.093 g/L(r = 0.999 8), the average recovery rate was 93.57% with RSD of 1.58% (n = 5);the good linearity relationship of cineole was during the range of 0.060 4-0.604 g/L( r = 0.999 7, the average recovery rate was 95.82% with RSD of 2.46% (n = 5). Conclusion The methods are simple and convenient with accurate and reliable detection results, good reproducibility and the effectively controllable quality of Xincangbishu Capsules.关键词
辛苍鼻舒胶囊/薄层色谱法/毛细管气相色谱法/质量标准Key words
Xincangbishu Capsules/ TLC/ CGC/ quality standard
分类
医药卫生
