中南民族大学学报:自然科学版2012,Vol.31Issue(2):50-56,7.
治疗急性缺血性脑中风神经保护药物研发的进展和展望
Research and Development of Neuroprotective Drugs for Acute Ischemic Stroke Therapy: Past and Future
摘要
Abstract
All attempts at treating strokes by pharmacologically reducing the human braing vulnerability to ischemia have failed, this is why stroke is still a leading cause of death, disability and massive socioeconomic loss worldwide. Over decades, research has failed to translate over 1,000 experimental treatments or new compounds from discovery in cells and animal models to use in humans. In this paper, we have reviewed several issues related to the mechanisms, key ideas for research and development of neuroprotective drugs and the problems. In addition, the research trends and new strategies and methods for the development of new drugs for acute ischemic stroke therapy have pointed out.关键词
急性缺血性脑中风/神经保护/药物治疗Key words
acute ischemic stroke/neuroprotective drug/pharmacological therapy分类
医药卫生引用本文复制引用
戴甲培,冯斌..治疗急性缺血性脑中风神经保护药物研发的进展和展望[J].中南民族大学学报:自然科学版,2012,31(2):50-56,7.基金项目
国家自然科学基金面上项目 ()
中南民族大学重点科研机构基金 ()