安徽农业科学2012，Vol.40Issue(21)：10894-10895,10945,3.
林蛙皮活性肽对小鼠免疫功能影响的试验研究
Experimental Investigation of Bioactive Peptides from the Skin of Rana chensinensis on Immune Function in Mice
巢警殳 1杜鹃 2刘雅娟3
作者信息
- 1. 吉林省长春市绿园区卫生局卫生监督所,吉林长春130062
- 2. 吉林医药学院公共卫生学院,吉林吉林132013
- 3. 吉林大学公共卫生学院,吉林长春130120
- 折叠
摘要
Abstract
[Objective] To observe the effects of bioactive peptide from the Skin of Rana chensinensis on immune function in normal mice. [Method] Mice were randomly divided into five groups, including negative group, positive group, low-dose group, rniddle-dose group and high-dose group, each group of ten. The mice were administrated for 28 days. Cellular immunity was detected by T-cell-proliferation MTT assay , humoral immunity was assessed by plaque forming ceil assay (PFC) and number of antibody-producing cells. [ Result] Bioactive peptide from the skin of Rana cheminen&is could obviously promote lymphocyte proliferation induced by ConA, increased antibody production in ceil number, and enhanced serum hemolyain antibody titer. [ Conclusion] Bioactive peptide from the skin of Rana ckensinensis could enhance cellular immunity and humoral immunity of mice.关键词
林蛙蛙皮/生物活性肽/免疫功能Key words
Skin of Rana chensinensis/ Bioactive peptide/ Immune function分类
农业科技引用本文复制引用
巢警殳,杜鹃,刘雅娟..林蛙皮活性肽对小鼠免疫功能影响的试验研究[J].安徽农业科学,2012,40(21):10894-10895,10945,3.
