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藏紫草化学成分及抑菌活性研究

黄艳 谭睿 王静 罗琴 崔文婷 吴梅 曹雨虹

安徽农业科学2012,Vol.40Issue(23):11553-11554,2.
安徽农业科学2012,Vol.40Issue(23):11553-11554,2.

藏紫草化学成分及抑菌活性研究

Study on Chemical Constituents and Antibacterial Activity of RADIX ONOSMATIS

黄艳 1谭睿 1王静 1罗琴 1崔文婷 1吴梅 1曹雨虹1

作者信息

  • 1. 西南交通大学生命科学与工程学院,四川成都610031
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摘要

Abstract

[Objective] To study the antibacterial activity of chemical constituents in RADIX ONOSMATIS. [Method] The chemical constituents were firstly extracted by 95% ethanol water to get ethanol extract (A). After that it was extracted to get petroleum ether extract (B), ethyl acetate extract (C) , and n - butanol extract (D) , C was isolated and purified by column chromatography, and their structures were identified by spectroscopic analysis. The antifungal activities of A, B, C and D were studied by K - B method, and the MIC was detected with two-times dilution method. [Result] Five compounds were isolated and identified as (3 -sitosterol, oleanolic acid, benzoic acid, ferulic acid and daucosterol. [ Conclusion] All the five compounds were isolated from this plant for the first time. A, B, C and D showed good antibacterial activity.

关键词

藏紫草( RADIX ONOSMATIS)/化学成分/抑菌活性

Key words

RADIX ONOSMATIS/ Chemical constituents/ Antibacterial activity

分类

农业科技

引用本文复制引用

黄艳,谭睿,王静,罗琴,崔文婷,吴梅,曹雨虹..藏紫草化学成分及抑菌活性研究[J].安徽农业科学,2012,40(23):11553-11554,2.

安徽农业科学

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