摘要
Abstract
Objective To evaluate the influence left ventricular function and systolic synchrony assessed by realtime three-dimensional echocardiography( RT-3DE ) before and after percutaneous coronary intervention therapy ( PCI ) in coronary heart disease patients. Methods By using RT-3DE, the three-dimensional parameters were repeatedly measured in thirty-eight patients with PCI treatment as CHD group before operation, 1st week and 3rd month after operation. Twenty-eight nomal subjects were enrolled as control group. The left ventricular end-diastolic volume( LVEDV ), left ventricular end-systolic volume( LVESV ), left ventricular ejection fraction( LVEF ), left ventricular stroke volume ( LVSV ), left ventricular peak ejection rate( PER ), left ventricular peak filling rate ( PFR), the time of minimal systolic volume of 16-segmental standard deviation( Tmsvl6-SD% ) and maximum difference ( Tmsvl6-Dif% ) were analyzed with software. Results Compared with the control group, LVEDV, LVESV,Tmsvl6-SD% ,Tmsvl6-Dif% were significantly higher ( P <0. 01 ), while LVEF, PER/EDV, PFR/EDV were lower ( P < 0. 01 ) in study group befroe operation. Compared with the preoperative group, LVEDV, LVESV, Tmsvl6-SD% , Tmsvl6-Dif% reduced significantly ( P < 0. 05,P < 0. 01 ), while LVEF, PER/EDV, PFR/EDV increased ( P <0. 05 ,P < 0. 01 ) in postoperative group. The bull-eye diagram showed that systolic timing delayed and systolic excursion attenuated in segments reduced significantly with CHD group after the operation. Conclusion Left ventricular remodeling could be found in patients with coronary heart dease and PCI might reverse the left ventricular remodeling somewhat. RT-3DE could be a new corrected valuable method of evaluating left ventricular function and systolic synchrony in patients with CHD before and after PCI.关键词
超声心动描记术/三维/冠状动脉介入/左室心功能Key words
echocardiography/ three-dimensional/ percutaneous coronary intervention/ ventricular function分类
医药卫生