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瓜石汤对初老大鼠卵巢Bcl-2表达影响的实验研究

郑君 李琪 孙凤平 吴克明

成都中医药大学学报2012,Vol.35Issue(2):43-44,2.
成都中医药大学学报2012,Vol.35Issue(2):43-44,2.

瓜石汤对初老大鼠卵巢Bcl-2表达影响的实验研究

Experimental Study on Infiuence of Gua-shi Decoction to Bcl-2 Expression of Primary Senile Rat Ovary

郑君 1李琪 2孙凤平 1吴克明3

作者信息

  • 1. 甘肃省中医院,甘肃兰州730050
  • 2. 河南省南阳市宛城区河南油田职工总医院,473400
  • 3. 成都中医药大学,四川成都610075
  • 折叠

摘要

Abstract

Objective: To discuss the mechanism of Gua-shi Decoction to delay the age of the primary senile rat ovary. Methods: 10 ~ 12 months old SD female rats whose oestrus elongation were set as primary senile female rat model Primary senile rats were derided randomly. After 4 weeks, weighed and sacrificed the rats. The ovaries were treated to observe expression of Bcl-2. Results: CuaShiTang could increase the expression of Bcl-2, compared with the model group, the high dose Gua-shi Decoction group have significant difference (P <0.05) . Conclusion: Cua-shi decoction could restrain ovary apoptosis. The effect may be one of the mechanism of Cua-shi Decoction delay the aging of primary senile rat ovary.

关键词

瓜石汤/初老雌性大鼠/卵巢/Bcl-2

Key words

Gua-shi Decoction/ primary senile female rat/ ovary / Bcl-2

分类

医药卫生

引用本文复制引用

郑君,李琪,孙凤平,吴克明..瓜石汤对初老大鼠卵巢Bcl-2表达影响的实验研究[J].成都中医药大学学报,2012,35(2):43-44,2.

基金项目

成都中医药大学2009年度博士创新基金资助项目. ()

成都中医药大学学报

OACSTPCD

1004-0668

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