成都中医药大学学报2012，Vol.35Issue(2)：45-50,6.
电针结合rTMS对焦虑抑郁障碍共病患者期待心理反应的影响
Effect of Electroacupuncture Combined with Repetitive Transcranial Magnetic Stimulation for Patients with Comorbid Anxiety and Depression on Psychological Reaction to Expectancy
摘要
Abstract
Objective: To explore the effect on brain electrical physiology of advanced (unction in psychological reaction to expectancy by combination of electroacupunctuie (EA) and repetitive transcranial magnetic stimulation (rTMS) to anxiety depression co-morbidity (CAD) . Methods: According with "China's mental disorders classification and diagnosis standard (the third edition)" (CCMD-3) Ninety cases of the participants were randomly divided into 3 groups. Thirty cases of the group of electroacupuncture combined with rTMS (EA + rTMS) was treated with electroacupuncture at Baihui (GV 20) , Yintang (EX-HN 3) , Shenting ( CV 24) . Shenmen (HT 7) and Neiguan (PC 6) mainly, combined with rTMS. The rTMS group with 30 cases was treated with simple rTMS. Both the EA + rTMS group and rTMS group were given according to the clinical conventional antidepressants and resistance to ami-ety drugs. Thirty cases of the foundation treatment group only with drugs. Separately, each group before the treatment and therapy after 10 days, were detected by the evoked potentials equipment of the Japanese Nihon Kohden recording (contingent negative variations, CNV) in Cz - A + channel , and comparing with 30 cases of normal control group. Results: ① Comparing with the control group, the latecy of starting point of expectancy wave in CNV (A point) had prolonged the trend in each treatment group before treatment, but no significant difference among four groups (P > 0.05) . The latecy of A point in EA + rTMS group is significantly reduced comparing with before treatment and the control group ( P < 0.05 ) . Before and after treatment in each treatment group had no significant differences, as well as among the control group and all treatment groups (P > 0.05) . ②The percentages of post imperative negative variation (PINV) regression baseline in the treatment groups before treatment were less than that in the control group (P<0.05). and no significant difference with the control group (P > 0.05) . Conclusion: EA combined with rTMS can significantly improve the patients with CAD to start process of psychological reaction to expectancy, and improve the spirit underpowered. EA, rTMS and antidepressant may reduce the patients brain arousal level, and ease patients anxiety symptoms.关键词
电针/重复经颅磁刺激/焦虑抑郁共病/关联性负变/随机对照试验Key words
Electroacupuncture/ repetitive transcranial magnetic stimulation/ comorbid anxiety and depression/ contingent negative variations/ randomized controlled Trial (RCT).分类
医药卫生引用本文复制引用
郑博,何林丽,邹可,蔡定均,杨君兰,郑重..电针结合rTMS对焦虑抑郁障碍共病患者期待心理反应的影响[J].成都中医药大学学报,2012,35(2):45-50,6.基金项目
国家自然科学基金面上项目资助(项目批准号:81173322) （项目批准号:81173322）
