成都中医药大学学报2012,Vol.35Issue(2):57-60,4.
愈创汤对低位单纯性肛瘘术后创面促愈机理的临床研究
The Clinical Research on Mechanism of “Yu-chuang Decoction”Healing Postoperative Wound of Low Anal Fistula
摘要
Abstract
Objective; To observe the impact and mechanism of " Yu-chuang Decoction" on postoperative wound healing of low simple anal fistula. Methods: 60 patients were randomly divided into treatment group and control group with 30 cases in each group. After conventional treatment, the treatment group and in combination with traditional Chinese medicine "Yu-chuang Decoction". Quantitative grading methods were used to observe in patients with rate of wound healing, wound healing time, granulation tissue growth, ECF changes. Anorectal manometry was used to observed recovery status of anorectal physiological function . Results; (1) Wound healing time of the treatment group were shorter than the control group (P<0.05) ; (2) Wound healing rate of treatment group were better than the control group (P <0.05); (3) Granulation growth of the treatment group were better than the control group (P<0. 05); (4) Before and after treatment , on anal function and anorectal dynamics index , the treatment group showed no significant difference (P>0.05), which control group showed significant difference (P<0.05); (5) ECF change of treatment group were better than the control group (P<0. OS) . Condussion: "Yu-chuang Decoction" has certain curative effect on wound repair of anal fistula operation. It can effectively shorten the wound healing time, and does not affect the function of anus. The healing of mechanism may related to endogenous ECF.关键词
愈创汤/低位单纯性肛瘘/创面愈合/机制Key words
Yu-chuang Decoction/ low simple anal fistula/ wound healing/ mechanism分类
医药卫生引用本文复制引用
畅立强,陆金根,曹永清..愈创汤对低位单纯性肛瘘术后创面促愈机理的临床研究[J].成都中医药大学学报,2012,35(2):57-60,4.基金项目
上海市重点学科建设基金资助项目(编号:T0304) (编号:T0304)