南方医科大学学报2012，Vol.32Issue(5)：730-733,4.DOI:10.3969/j.issn.1673-4254.2012.05.033
低频超声促进哺乳期大鼠泌乳的实验研究
Low frequency ultrasound promotes lactation in lactating rats
摘要
Abstract
Objective To investigate the effect of low-frequency ultrasound in promoting milk secretion in rats during lactation.Methods Twenty-four lactating SD rats feeding 10 suckling rats each were randomly allocated into 3 groups,namely the control group (with sham irradiation),5 min group (with ultrasonic irradiation of the breast for 5 min daily),and 10 min group (irradiation for 10 min daily).The mammary glands of the rats were consistently irradiated by low-frequency ultrasound (40 kHz,0.26 W/cm2) for 7 days since the 2nd day after delivery.The milk yield,average body weight gain of the offspring,mammary gland index,serum prolactin (PRL) and breast histology were examined.Results The milk yield,body weight gain of offspring,mammary gland index and serum PRL concentration in 10 min group were significantly greater than those in the control group and 5 min group (P0.05).Compared with the other two groups,the 10 min group showed significantly increased acinar gland expansion and acinar number.Conclusion Low-frequency ultrasound can promote milk secretion in iactating rats,suggesting its potential as a new approach of physical therapy for promoting milk secretion.关键词
低频超声/大鼠/催乳素/泌乳Key words
low-frequency ultrasound/rats/prolactin/milk secretion分类
医药卫生引用本文复制引用
汪琴,乔海,白晋..低频超声促进哺乳期大鼠泌乳的实验研究[J].南方医科大学学报,2012,32(5):730-733,4.基金项目
国家自然科学基金(31000435) （31000435）
国家重点基础研究发展计划(973计划)(2011CB707902) （973计划）
国家重大仪器专项(81127901) （81127901）
