南方医科大学学报2012，Vol.32Issue(7)：991-994,4.DOI:10.3969/j.issn.1673-4254.2012.07.019
三维适形放疗和适形调强放疗技术对鼻咽癌放疗后颞颌关节损伤的影响
Comparison of temporomandibular joint injuries after three-dimensional conformal and intensity-modulated radiotherapies for nasopharyngeal carcinoma
摘要
Abstract
Objective To compare the radiation injuries of the temporomandibular joint (TMJ) following three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) in patients with nasopharyngeal carcinoma (NPC). Methods Thirty-nine NPC patients without previous radiotherapy underwent 3D-CRT and another 32 received IMRT in our institute. The distance between the 2 dens incisivus medialis (DDIM) and LENT SOMA criteria were employed to evaluate TMJ injuries, clinical outcomes, and the performance-to-price ratios. Results The short-term local response rates were similar between the two groups (P=0.878). The mean radiation doses of the TMJ were significantly higher in 3D-CRT group than in IMRT group (57.06 us 40.90 Gy, P<0.001). The DDIM showed significant changes in 3D-CRT groups after the radiotherapy (P<0.05). No significant difference was found in the TMJ injuries between the two groups according to the SOMA criteria (P>0.05). Conclusion Radiation injuries of the TMJ are tolerable in both 3D-CRT and IMRT groups, and 3D-CRT is a more economic choice for patients who can not afford IMRT.关键词
鼻咽肿瘤/三维适行放疗/调强适行放射治疗/颞颌关节/放射损伤Key words
nasopharyngeal neoplasms/ three-dimensional conformal radiotherapy/ intensity-modulated radiation therapy/ temporomandibular joint/ radiation damage分类
医药卫生引用本文复制引用
陈冬平,余意,齐斌,刘锦全,李铭仪,梁玉莹..三维适形放疗和适形调强放疗技术对鼻咽癌放疗后颞颌关节损伤的影响[J].南方医科大学学报,2012,32(7):991-994,4.基金项目
广东省医学科研基金(A2011287) （A2011287）
