南方医科大学学报2012，Vol.32Issue(7)：1037-1041,5.DOI:10.3969/j.issn.1673-4254.2012.07.029
基于亚毫米CT的三维可视化技术在宫颈癌诊治中的应用
Application of micro-computed tomography-based 3D visualization in diagnosis and treatment of cervical cancer
摘要
Abstract
Objective To define the optimal development time of micro-computed tomography (micro-CT) venography in cervical cancer patients and establish 3D CT-based digital pelvic model of the patients. Methods Thirty patients with cervical cancer stratified by F1GO surgical staging underwent micro-CT scanning of the arterial phase and the venous phase with a delay time of 70, 90 and 120 s. The images were interpreted independently by two experienced radiologists to define the optimal development time in venous phase and establish the imaging diagnosis. Based on the pelvic CT scan data, we segmented the images using the abdominal medical image-3D visualization system followed by 3D image reconstruction to establish the 3D digital pelvic model using FreeForm Modeling System to modify the reconstructed images. Results The optimal images were obtained by scanning with a 90-sec delay time. Micro-CT was not sensitive to IB1 phase or earlier phases (1/5), but efficient in advanced stages (≥IB2 phase). In our cases, 25 were diagnosed by micro-CT with a diagnostic accuracy of 64%. Based on these CT data, the pelvic 3D model covering the main organs, vessels, cervical neoplasm, and supplying vessels of the tumor in the pelvic cavity were successfully reconstructed to allow spatial observations of the uterus and the neighboring organs. Conclusion The 3D digital pelvic model reconstructed provides a means for staging cervical cancer and facilitates further surgical simulation studies.关键词
宫颈癌/女性盆腔数字化模型/三维重建/数字化Key words
cervical cancer/ pelvic 3D digital image model/ 3D reconstruction/ digitization分类
医药卫生引用本文复制引用
朱洪磊,何援利,王显龙,李湘元,彭冬先,王雪峰,江永焰,李静..基于亚毫米CT的三维可视化技术在宫颈癌诊治中的应用[J].南方医科大学学报,2012,32(7):1037-1041,5.基金项目
广东省医学科研基金(B2008116) （B2008116）
广州市海珠区科技计划项目(2010-Y-11) （2010-Y-11）
