南方医科大学学报2012，Vol.32Issue(8)：1154-1156,3.DOI:10.3969/j.issn.1673-4254.2012.08.18
血液炎症标记物在诊断小儿急性阑尾炎中的意义
Value of blood inflammatory markers in the diagnosis of acute appendicitis in children
摘要
Abstract
Objective To investigate the value of serum inflammatory markers in the diagnosis of acute appendicitis (AA) in children. Methods Blood samples were collected from 51 children with AA and 16 children with nonsurgical abdominal pain (NSAP) to examine white blood cell count (WBC), serum C-reactive protein (CRP), interleukin-6, and tumor necrosis factor-α (TNF-α). Results WBC count, CRP, IL-6 and TNF-α increased significantly in children with severe AA (phlegmonous or gangrenous, and perforated appendicitis). ROC curves showed that IL-6 or TNF-α had a greater contribution than WBC count to the diagnosis of severe appendicitis. Conclusion IL-6 and TNF-α can provide complementary information to assist the clinical decision of emergency operation for children with AA.关键词
急性阑尾炎/炎症标记物/白细胞介素6/肿瘤坏死因子-aKey words
acute appendicitis/ inflammatory markers/ diagnosis分类
医药卫生引用本文复制引用
黄党生,韩溟,谢扬..血液炎症标记物在诊断小儿急性阑尾炎中的意义[J].南方医科大学学报,2012,32(8):1154-1156,3.基金项目
国家自然科学基金(81172088) （81172088）
广东省医学科研基金(粤卫[2011]74号) （粤卫[2011]74号）
