福建师范大学学报（自然科学版）2012，Vol.28Issue(4)：76-81,6.
Frizzed家族基因mRNA在小鼠动情周期卵巢组织中的表达规律
Relative mRNA Expression Levels of Frizzed Family Genes in Mice Ovaries at Different Estrous Stages
摘要
Abstract
Real-time Q-PCR was used to analyze the relative expression levels of Frizzed 1-10 mRNAs in the mice ovaries at different estrous stages. The results showed that they had different expression patterns except Frizzed 8. Expressions of Frizzed 1 and 2 were the highest in proestrus and both were about 4 times higher than those in diestrus (P < 0. 05) . Frizzed 3 was 1.5 fold higher in proestrus and diestrus than those in the other two periods (P < 0. 05) . Frizzed 4 was found significantly higher expression in estrus, which is about 3 fold than that in diestrus (P < 0.05) . Frizzed 5 was marked higher in diestrus than those in proestrus and estrus, being approximately 5 times higher than that in estrus (P < 0. 05) . Frizzed 7 was similar to Frizzed 5, about 4 fold higher than the level in proestrus (P < 0. 05). Frizzed 10 expression in proestrus was about more than 3 times higher than that in estrus (P < 0. 05) , but Frizzed 6 and 9 were no significant difference during the estrous cycle (P > 0. 05) . These results suggested that Frizzeds, were widely and differentially expressed in estrous ovary and Frizzed 1-4 may play a more important role in the development of follicle during the estrous cycle.关键词
Frizzed/动情周期/卵巢/小鼠Key words
Frizzed/ estrous cycle/ ovary/ mouse分类
生物科学引用本文复制引用
王少兵,徐银学,王正朝..Frizzed家族基因mRNA在小鼠动情周期卵巢组织中的表达规律[J].福建师范大学学报（自然科学版）,2012,28(4):76-81,6.基金项目
国家863高技术研究发展计划资助项目(2006AA10Z136) （2006AA10Z136）
国家自然科学基金资助项目(31101032) （31101032）
教育部博士点基金资助项目(20113503120002) （20113503120002）
福建省自然科学基金资助项目(2011J01144) （2011J01144）
福建省教育厅杰出青年基金资助项目(AJ11041) （AJ11041）
芜湖职业技术学院引进人才科研基金资助项目 （）
