辐射防护2012,Vol.32Issue(5):296-300,5.
极低频电磁场暴露对大鼠学习记忆功能影响的研究
Effect of Exposure to ELF-EMFs on Learning and Memory Ability of Rats
王东 1郭键锋 1孔令丰 2郭兴明3
作者信息
- 1. 深圳市环境监测中心站,广东深圳518049
- 2. 广东省环境保护厅,广州510630
- 3. 重庆大学,重庆400030
- 折叠
摘要
Abstract
To explore the effect of exposure to extremely low frequency electromagnetic fields(ELFEMFs) of working environment on learning and memory of rats and changes of their hippocampus neurons,an 50 Hz EMFs exposure system was developed.40 Wistar rats equally divided into two groups(Group 1 and Group 2) were exposed to electromagnetic fields of 5 kV/m,78 μT 50 Hz and of 5 kV/ m,100 μT 50 Hz respectively for 8 consecutive weeks 8 hours per day and 5 days per week.Then their learning and memory ability and hippocampus pathological changes were studied as well as the neuron apoptosis in hippocampus.Results showed that exposure to ELF-EMFs of certain intensity for a period can cause notable injure to rat’s memory;the learning and memory ability of the sham exposed rats is significantly better than the exposed rats(p〈0.05);the neurobehavioral dysfunction was prior to histopathological damage and hippocampus neuron cell injury;and the magnetic field in particular had great impact on the above findings.关键词
极低频电磁场/学习记忆/细胞凋亡/大鼠Key words
ELF-EMFs/learning and memory/apoptosis/rat分类
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王东,郭键锋,孔令丰,郭兴明..极低频电磁场暴露对大鼠学习记忆功能影响的研究[J].辐射防护,2012,32(5):296-300,5.