分析测试学报2012，Vol.31Issue(7)：853-857,5.DOI:10.3969/j.issn.1004-4957.2012.07.017
聚对氨基苯磺酸/石墨烯复合修饰电极对尿酸的选择性灵敏测定
Selective and Sensitive Determination of Uric Acid on PABSA/GN Composite-modified Glassy Carbon Electrode
摘要
Abstract
A PABSA/GN/GCE composite-modified electrode was fabricated by using a graphene nanosheets(GN) modified glassy carbon electrode ( GCE) electropolymerized with p-aminobenzene sulfonic acid( PABSA). The electrochemical behaviors of uric acid( UA) and ascorbic acid( AA) on the nanocomposites-modified electrode were investigated. Compared with PABSA/GCE and GN/GCE, the PABSA/GN/GCE improved the resolution and the sensitivity for the determination of UA in the presence of AA. In 0. 1 mol/L phosphate buffer solution (pH 7. 0), a peak to peak separation of 344 mV was observed, which enabled the selective determination of UA. The peak currents obtained from DPV were linearly related to concentrations of UA in the range of 1. 0×10-7 - 8. 0×10 -4 mol/L. The detection limit was 4. 5×10-8 mol/L. The nanocomposites-modified electrode was adopted for the detection of UA in the human urine with satisfactory result.关键词
对氨基苯磺酸/石墨烯/修饰电极/选择性测定/尿酸/抗坏血酸Key words
p-aminobenzene sulfonic acid/ graphene nanosheets/ modified electrode/ selective determination/ uric acid(UA)/ ascorbic acid(AA)分类
化学化工引用本文复制引用
孙娜,王宗花,夏建飞,郭新美,张菲菲,夏延致,李延辉..聚对氨基苯磺酸/石墨烯复合修饰电极对尿酸的选择性灵敏测定[J].分析测试学报,2012,31(7):853-857,5.基金项目
国家自然科学基金(20975056,81102411) （20975056,81102411）
山东省自然科学基金(ZR2011BZ004,ZR2011BQ005) （ZR2011BZ004,ZR2011BQ005）
NSFC-JSPS中日合作与交流项目(21111140014) （21111140014）
生命分析化学国家重点实验室开放基金(SKLACLS1110) （SKLACLS1110）
山东省泰山学者资助项目(TS20070711) （TS20070711）
