高等学校化学学报2012，Vol.33Issue(7)：1438-1443,6.DOI:10.3969/j.issn.0251-0790.2012.07.013
CCl4对左旋氧氟沙星超声降解的影响
Effect of CCl4 on Antibiotics Levofloxacin' s Ultrasonic Degradation
摘要
Abstract
The ultrasonic degradation of quinolone antibiotics levofloxacin in water with CC14 enhancement was investigated. The effects of CC14.dosage, ultrasonic power, pH value and initial concentration of levofloxacin were discussed. The products were examined by HPLC and LC-MS/MS. The results.indicated that the ultrasonic degradation of levofloxacin was obviously enhanced by CC14 addition; the degradation efficiency increased from 1. 9% to 69. 2% with CC14 dosage changed from 0 to 0. 06% ( volume fraction). The enhancement effect was attributed to the increasing · OH radical concentration and formation of chlorine-containing radicals in the presence of CC14 during ultrasonic processes. Levofloxacin degradation efficiency by ultrasonic in the presence of CC14 increased with the increasing of ultrasonic power in 100-200 W. The pH values of solution had prominent effect on levofloxacin degradation, while the initial concentration of levofloxacin had a negative effect. The temperature between 33-49 ℃ was found to be favorable to levofloxacin degradation. Moreover, HPLC analysis showed that two main by-products were simultaneously produced in the course of the ultrasonic degradation of levofloxacin in addition of CC14, the two products were confirmed by LC-MS/MS analysis.关键词
喹诺酮类抗生素/左旋氧氟沙星/超声降解/四氯化碳Key words
Quinolone antibiotics/ Levofloxacin/ Ultrasonic degradation/ Carbon tetrachloride分类
化学化工引用本文复制引用
魏红,李娟,李克斌,孙剑宇,赵锋..CCl4对左旋氧氟沙星超声降解的影响[J].高等学校化学学报,2012,33(7):1438-1443,6.基金项目
国家自然科学基金(批准号:51009115)和陕西省科技计划项目(批准号:2010JQ5008)资助. （批准号:51009115）
