国际医药卫生导报2012，Vol.18Issue(13)：1866-1868,3.DOI:10.3760/cma.j.issn.1007-1245.2012.13.010
电视纵隔镜和多排螺旋CT诊断非小细胞肺癌纵隔淋巴结转移的对比研究
Video-mediastinoscopy and multi-slice spiral CT for the diagnosis of medisstinal lymphatic metastasis of non-small cell lung cancer
摘要
Abstract
Objective To cpmpare the clinical value of video-mediastinoscopy and multi-slice spiral CT ( MSCT ) in determining mediastinal lymphatic metastasis of non-small eel] lung cancer ( NSCLC ).Methods From October 2009 to August 201 I,48 patients with NSCLC undergoing surgical treatment were preoperatively investigated by video-mediastinoecopy and MSCT in our hospital.Pathological diagnosis of mediastinal lymph nodes dissection accepted as the gold standard to examine the sensitivity and specificity of video-mediastinoscopy and MSCT.Results A total of 11 of the 48 patients with NSCLC were pathologically confirmed as mediastinal lymphatic metastasis.8 patients with mediastinal lymphatic metastasis were accurately detected by CT,with an accuracy of 89.58％,while 10patients were accurately confirmed by video-mediastinoscopy,with an accuracy of 97.92％.The accuracy of video-mediastinoscopy was superior to that of MSCT ( P＜ 0.05 ).The sensitivity,specificity,false negative rate,false positive rate,positive predictive value,negative predictive value,and Youden’s index for detecting mediastinal lymphatic metastasis were 72.73％,94.59％,27.27％,5.41％,80.00％,92.11％,and 67.31by CT,respectively,versus 90.91％,100.00％,9.09％,0.00％,100.00％,97.37％,and 90.90％ by videomediastinoscopy,respectively.Conclusions Both video-mediastinoscopy and MSCT can detect mediastinal lymphatic metastasis of lung cancer; and video-mediastinoscopy has a better sensitivity and and better accuracy.of the 48 patients with NSCLC were pathologically confirmed as mediastinal lymphatic metastasis.8 patients with mediastinal lymphatic metastasis were accurately detected by CT,with an accuracy of 89.58％,while 10patients were accurately confirmed by video-mediastinoscopy,with an accuracy of 97.92％.The accuracy of video-mediastinoscopy was superior to that of MSCT ( P＜ 0.05 ).The sensitivity,specificity,false negative rate,false positive rate,positive predictive value,negative predictive value,and Youden’s index for detecting mediastinal lymphatic metastasis were 72.73％,94.59％,27.27％,5.41％,80.00％,92.11％,and 67.31by CT,respectively,versus 90.91％,100.00％,9.09％,0.00％,100.00％,97.37％,and 90.90％ by videomediastinoscopy,respectively.Conclusions Both video-mediastinoscopy and MSCT can detect mediastinal lymphatic metastasis of lung cancer; and video-mediastinoscopy has a better sensitivity and and better accuracy.关键词
纵隔镜/多排螺旋CT/非小细胞肺癌Key words
Video-mediastinoscopy/Multi-slice spiral CT/Non-small cell lung cancer引用本文复制引用
伍硕允,卢珠明,兰勇,叶敏,庞文广,林志潮,黄文海,庞景灼..电视纵隔镜和多排螺旋CT诊断非小细胞肺癌纵隔淋巴结转移的对比研究[J].国际医药卫生导报,2012,18(13):1866-1868,3.基金项目
江门市科学技术立项(2011-8978) （2011-8978）
