国际医药卫生导报2012，Vol.18Issue(15)：2248-2250,3.DOI:10.3760/cma.j.issn.1007-1245.2012.15.048
无抽搐电休克治疗难治性精神分裂症临床观察
Modified electroconvulsive therapy for refractory schizophrenia
黄隆光 1吕亚华 1徐文耀 1刘锋 1高建箱 1邹艳频1
作者信息
摘要
Abstract
Objective To evaluate the clinical efficacy of modified electroconvulsive therapy ( MECT ) for refractory schizophrenia.Methods 100 patients with refractory schizophrenia who had been hospitalized during the period of June 2010 to June 2011 were treated With antipsychotic medication and MECT.The Positive and Negative Syndrome Scale ( PANSS )were used to evaluate the clinical effect and the Treatment Emergent Symptom Scale ( TESS ) was used to determine adverse reactions.Results The effective rate was 9％ on week 1,29％ on week 4,and 56％ on week 8.The total scores on the PANSS,positive symptoms,negative symptoms,and general psychopathologic scores were significantly decreased on weeks 4 and 8 ( P≤0.05 or P≤0.01 ).There was no statistical difference in the scores on the TESS ( P＞ 0.05 ).Adverse reactions occurred slightly during treatment.Conclusions Antipsychotic medication combined with modified electroconvulsive therapy is effective for refractory schizophrenia without increased adverse reactions.关键词
无抽搐电休克治疗/难治性精神分裂症/精神分裂症Key words
Modified electroconvulsive therapy/Refractory schizophrenia/Schizophrenia引用本文复制引用
黄隆光,吕亚华,徐文耀,刘锋,高建箱,邹艳频..无抽搐电休克治疗难治性精神分裂症临床观察[J].国际医药卫生导报,2012,18(15):2248-2250,3.
