国际医药卫生导报2012，Vol.18Issue(16)：2319-2321,3.DOI:10.3760/cma.j.issn.1007-1245.2012.16.001
香莲外洗液对念珠菌葡萄糖消耗的影响分析
Study on the effect of Xianglian solution to glucose utilization of candida
摘要
Abstract
Objective To observe the effect of Xianglian solution to glucose utilization of candida,and study the inhibition effect of Xianglian solution to candida.Methods We determined glucose utilization of three candida isolates effected by different density of Xianglian solution and fluconazol,to identify the inhibition effect of Xianglian solution to candidas.The three candida isolates included type strains ATCC22019,ATCC6258 and SC5314 which were resistive to antifungal drugs.Results Xianglian solution (density≥0.98 mg/ml) cut down glucose utilization of three isolates visibly,and activity was almost similar.Fluconazol cut down glucose utilization of type strains ATCC22019 and ATCC6258(density was 4 μ g/ml and 32 μ g/ml respectively).And fluconazol (density 128 μ g/ml) didn't cut down glucose utilization of type strain SC5314.Conclusions Xianglian solution (density≥0.98mg/ml) can cut down glucose utilization of three isolates visibly,and display obvious inhibition effect to ATCC6258 and SC5314 which are resistive to fluconazol.Xianglian solution is helpful for treatment of intractable mycosis.关键词
香莲外洗液/氟康唑/葡萄糖消耗Key words
Xianglian solution/Fluconazol/Glucose utilization引用本文复制引用
张文,柏彩英,周强,范瑞强..香莲外洗液对念珠菌葡萄糖消耗的影响分析[J].国际医药卫生导报,2012,18(16):2319-2321,3.基金项目
“十一五”国家科技支撑计划(2008BA153B041) （2008BA153B041）
