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枳实破壁粉粒对小肠推进及急性毒性作用的研究

林大都 成金乐 陈健文 徐吉银 刘培庆 黄芝瑛

广东药学院学报2012,Vol.28Issue(4):435-437,3.
广东药学院学报2012,Vol.28Issue(4):435-437,3.DOI:10.3969/j.issn.1006-8783.2012.04.020

枳实破壁粉粒对小肠推进及急性毒性作用的研究

Effect of the wall-broken spore power of Aurantii Fructus Immaturus on the intestinal transit and acute toxicity test in mice

林大都 1成金乐 1陈健文 2徐吉银 1刘培庆 2黄芝瑛2

作者信息

  • 1. 中山市中智药业集团有限公司,广东中山528437
  • 2. 中山大学药学院,广东广州510006
  • 折叠

摘要

Abstract

Objective To study the effect of the wall-broken spore power of Aurantii Fructus Immaturus on the intestinal transit and acute toxicity test in mice. Methods The effect of the wall-broken spore power of Aurantii Fructus Immaturus on the intestinal transit was evaluated by the small intestinal carbon transit rate, which toxicity was detected by maximum dosage test. Results The clinical equivalent dose of the wall-broken spore power of Aurantii Fructus Immaturus showed a prominent promotion effect on intestinal transit. Half dose of the wall-broken spore power worked equally to its cut crude dings. And no acute toxicity in mice occurred. Conclusion The wall-broken spore power of Aurantii Furctus Immaturus exhibits a beneficial effect on intestinal transit with no acute toxicity.

关键词

枳实/破壁粉粒/小肠推进作用/急性毒性

Key words

Aurantii Furctus Immaturus/ wall-broken spore power/ the effect on intestinal transit/ acute toxicity

分类

医药卫生

引用本文复制引用

林大都,成金乐,陈健文,徐吉银,刘培庆,黄芝瑛..枳实破壁粉粒对小肠推进及急性毒性作用的研究[J].广东药学院学报,2012,28(4):435-437,3.

基金项目

广东省粤港关键领域重点突破招标项目(20080106-2) (20080106-2)

广东省科技计划项目(2008B080101034) (2008B080101034)

中山市科技强企支撑计划项目(20092A113) (20092A113)

广东药学院学报

OACSTPCD

1006-8783

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