神经损伤与功能重建2012，Vol.7Issue(5)：321-323,384,4.DOI:10.3870/sjsscj.2012.05.003
全麻下顺式阿曲库铵对大鼠面神经复合肌肉动作电位的影响
Effects of Cisatracurium on Compound Muscle Action Potentials of Facial Nerves in Rats Under General Anesthesia
摘要
Abstract
Objective:To study the effects of cisatracurium on compound muscle action potentials (CMAPs) of facial nerves in rats. Methods: A total of 40 SD rats were randomly divided into experimental and control groups. Cisatracurium (0. 186 mg/kg) was injected in rats in the experimental group,and isotonic saline of same volume was applied in the control group, through the external jugular vein. The facial nerves were stimulated at 5 minutes intervals before and after injection and the CMAPs of the buccinator muscle were recorded. Results: The peak-to-peak values and latencies did not show significantly changes in the control group,but significant differences between the two groups were observed 5 minutes after injection (P<0. 05). The CMAPs demonstrated three phasic changes in the experimental group. Conclusion: Cisatracurium is able to affect the CMAPs of facial nerves significantly.关键词
顺式阿曲库铵/全身麻醉/面神经/复合肌肉动作电位Key words
cisatracurium/ general anesthesia/ facial nerve/ compound muscle action potential分类
医药卫生引用本文复制引用
臧光辉,孟祥虎,樊龙昌,李新华,刘继红,张传汉,罗爱林,田玉科..全麻下顺式阿曲库铵对大鼠面神经复合肌肉动作电位的影响[J].神经损伤与功能重建,2012,7(5):321-323,384,4.基金项目
国家自然科学基金(No.30901404) （No.30901404）
