高校化学工程学报2012,Vol.26Issue(4):575-580,6.
介电材料辅助的微波冷冻干燥的数值模拟
Numerical Simulation on Freeze Drying with Dielectric Material Assisted Microwave Heating
摘要
Abstract
The effects of the dielectric material on the microwave freeze-drying process were theoretically studied by mathematically solving the heat and mass transfer model considering the hygroscopic effect with a moving boundary in the porous media. Sintered silicon carbide (SiC) was used as the dielectric material, and the mannitol, a typical pharmaceutical excipient, was selected as the solute in aqueous solution. Simulation results show that the dielectric material can significantly enhance the microwave freeze drying rate under the experimental operating conditions, especially when the solid content in the freeze dried solution is very low or the solid product has a very small dielectric loss factor. Comparisons of the drying curves display good agreements between experimental measurements and model predictions. Based on the profiles of ice saturation and temperature, mechanisms of heat and mass transfer inside the material were analyzed, and the drying rate-controlling factor was discussed.关键词
微波冷冻干燥/介电材料/干燥曲线/多孔介质/传热传质Key words
microwave freeze drying/ dielectric material/ drying curve/ porous media/heat and mass transfer分类
化学化工引用本文复制引用
王维,许英梅,马鸿信,陈国华..介电材料辅助的微波冷冻干燥的数值模拟[J].高校化学工程学报,2012,26(4):575-580,6.基金项目
国家自然科学基金(21076042/B060302) (21076042/B060302)
香港研资局(RGC)基金(HKUST 600704/C4586) (RGC)
大连民族学院自主科研基金(DC12010209). (DC12010209)