南方农业学报2012，Vol.43Issue(7)：1046-1048,3.DOI:10.3969/j:issn.2095-1191.2012.07.1046
乳头管灌注脂多糖对家兔抗氧化能力的影响
Effect of lipopolysaccharide (LPS) infusion via teat canal on antioxidant capacity in rabbits
摘要
Abstract
[Objective]Mastitis model was established to study the effects of LPS infusion via teat canal on antioxidant caputity in rabbils so as to provide theoretical information for applying antioxidant drugs to prevent and treat mastitis. [Method ]Primiparous rabbits were injected with 0.150 and 0.075 mg/kg LPS, reclal temperature, breast swelling degree, and SOD activity, MDA content and T-AOC. in serum were detected and recorded in 2 hours before perfusion, and 6, 12, 24, 48, 72 hours as well as 5, 7 days after perfusion. [Result] After LPS perfusion, temperature of primiparous rahbils soared to over 40.00℃ with harder breasts and yellowish white viscous milk. Moreover, SOD activity, MDA content and T-AOC in serum showed a variation trend of parabola, which was up first and then down, after the injured breast was cured, SOD activity, MDA content and T-AOC returned to the level before LPS perfusion. [Conclusion]The dynamic trend of SOD activity. MDA content and T-AOC conformed with the changes of mastitis, hence the three indicators should be used in monitoring breast health and as candidate parameters for mastitis diagnose.关键词
家兔/乳房炎/乳头管灌注/脂多糖/抗氧化能力Key words
rabbit/mastitis/infusion via teat canal/LPS/antioxidant capacity分类
农业科技引用本文复制引用
邓华学,雍康,张传师,杨庆稳..乳头管灌注脂多糖对家兔抗氧化能力的影响[J].南方农业学报,2012,43(7):1046-1048,3.基金项目
重庆市教育委员会科研项目(KJ111902) （KJ111902）
