郑州大学学报（医学版）2012，Vol.47Issue(4)：537-539,3.DOI:10.3969/j.issn.1671-6825.2012.04.036
前列腺特异性抗原相关变数与前列腺癌Gleason评分及临床分期的关系
Relationship between prostate specific antigen related variables and Gleason score and clinical stage of prostate cancer
王道元 1乔保平 1孙如坤 1辛航 1王雷阳1
作者信息
- 1. 郑州大学第一附属医院泌尿外科,郑州,450052
- 折叠
摘要
Abstract
Aim : To explore the relationship between prostate specific antigen related variables and Gleason score and clinical stage in patients with prostate cancer. Methods: The clinical data from 125 cases of prostate cancer diagnosed by biopsies were collected, and the correlation of FPSA , F/TPSA and PSAD with Gleason score and clinical stage was analyzed. Results: FPSA was positively correlated with Gleason score ( rs =0. 499 , P < 0. 001 ) , but negatively correlated with clinical stage ( rs = - 0. 300 , P < 0. 001) for prostate cancer patients ; PSAD was also positively correlated with Gleason score ( rs = 0. 616 ,P < 0. 001 ) , but not correlated with clinical stage ( rs = - 0. 128 ,P = 0. 155 ) for prostate cancer patients; F/TPSA was negatively correlated with clinical stage ( rs = -0.417,P<0. 001 ) , but weakly correlated with Gleason score ( rs = 0. 182 ,P = 0. 042) for prostate cancer patients. Conclusion ;FPSA could be used as a reference index in pathological grading and clinical staging for prostate cancer patients ; PSAD could be used as a reference index in pathological grading and F/TPSA could be used as a reference index in clinical staging for prostate cancer patients.关键词
前列腺癌/前列腺特异性抗原/前列腺特异性抗原密度/Gleason评分/临床分期Key words
prostate cancer/ prostate specific antigen / prostate specific antigen density / Gleason score / clinical stage分类
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王道元,乔保平,孙如坤,辛航,王雷阳..前列腺特异性抗原相关变数与前列腺癌Gleason评分及临床分期的关系[J].郑州大学学报（医学版）,2012,47(4):537-539,3.
