中医学报2012，Vol.27Issue(7)：791-792,2.
宫瘤平急性毒性实验
Acute Toxicity Tests of Gongliuping
曾令菊 1罗云2
作者信息
- 1. 湖北省中医院光谷院区,湖北武汉430074
- 2. 湖北中医药大学,湖北武汉430061
- 折叠
摘要
Abstract
Objective:To provide the toxicology basis of formulary development and clinical application for gongliuping. Methods:Observe the acute toxicity reaction and death information in short time after a large dose of physic liquor. Determine the median lethal dose ( LD50) or maximum tolerated dose. Results: No animal dies, neither do animals show any toxic effects during the observation period. So we failed lo detect the LDSO. The measured ig in mice of the maximum tolerance is more than 520 g · kg ‐1, 335 times to adults dosage. The ig agent in rats of the maximum tolerance is more than 195 g · kg‐1 ,126 times to adult daily clinical doses. Conclusion:The experiment suggests that the self - made gongliuping prescription is safe with a low toxicity.关键词
宫瘤平/最大耐受量/半数致死量/急性毒性实验Key words
gongliuping/maximum tolerable dose/median lethal dose/acute toxicity tests分类
医药卫生引用本文复制引用
曾令菊,罗云..宫瘤平急性毒性实验[J].中医学报,2012,27(7):791-792,2.
