湖南中医药大学学报2012，Vol.32Issue(3)：10-13,4.DOI:10.3969/j.issn.1674-070X.2012.03.003.010.04
水溶性黑柄炭角菌肽的体外抗氧化活性
Anti-oxidative activity of water-soluble peptides from Xylaria nigripes in vitro
摘要
Abstract
Objective To study anti-oxidative activity of water-soluble peptides from Xylaria nigripes (XNP) in vitro.Methods The anti-oxidative activity of water-soluble peptides from XNP were studied entirely by measuring scavenging rate of water-soluble peptides from XNP on super-oxide anion generated by pyrogallol autuxidaliun,hydroxyl free radical in Fenton reaction and DPPH free radical,and their reducing power and inhabiting peroxidation of liposomes ability.Results Water -soluble peptides from XNP could significantly reduce pyrogallol autoxidation rate,had highly scavenging capacity of hydroxyl free radical,and had dose dependent in scavenging DPPH free radical scavenging.Their IC50 were 10,0.49 mg/mL and 16.3 ug/mL respectively.Futher research showed that water-soluble peptides from XNP had certain reducing power increased as concentration increased,they also could inhibit the peroxidation of liposomes.Conclusion Water-soluble peptides from XNP was a good anti-oxidant in vitro test.关键词
黑柄炭角菌/肽/抗氧化/体外试验Key words
Xylaria nigripes/peptides/anti-oxidation/in vitro test分类
医药卫生引用本文复制引用
翁榕安,胡劲松,翁诗玉..水溶性黑柄炭角菌肽的体外抗氧化活性[J].湖南中医药大学学报,2012,32(3):10-13,4.基金项目
湖南省自然科学基金资助项目(10JJ3039). （10JJ3039）
