四川大学学报（医学版）2012，Vol.43Issue(4)：547-552,6.
不同代谢综合征诊断标准运用于四川地区人群的比较分析
Comparison of Different Diagnostic Criteria for Metabolic Syndrome in Sichuan Population
摘要
Abstract
Objective To evaluate the consistency of the diagnostic criteria for metabolic syndrome (MS) proposed by World Health Organization 1999 (WHO1999), National Cholesterol Education Program Adult Treatment Panel Ⅲ 2005 (ATP Ⅲ 2005), Chinese Diabetes Society 2004 (CDS2004), and International Diabetes Federation 2005 (IDF2005) , and to identify a more applicable one for people in Sichuan. Methods A cross-sectional survey on MS was conducted in Sichuan. A total of 3511 participants were recruited through multistage cluster random sampling. A questionnaire was administered to the participants, along with physical examinations and laboratory tests involving oral glucose tolerance test and lipid profiles. The MS patients were identified by the above-mentioned diagnostic criteria. Results According to the ATPⅢ (2005), the prevalence and age-adjusted prevalence of MS were 22. 4% and 19. 8% in Sichuan population respectively, significantly higher than those identified by the other 3 diagnostic criteria. The prevalence of MS increased with age. Men had higher prevalence of MS than women (P<0. 05) according to the CDS(2004) and WHO(1999). But women had higher prevalence of MS than men according to the IDF (2005) and no gender difference in the prevalence of MS existed according to the ATP Ⅲ (2005). No significant difference was found in the prevalence of MS between the Han ethnicity and the Yi ethnicity regardless which diagnostic criteria were adopted. The 4 MS diagnostic criteria reached a consistency of 81. 17%. The highest consistency (95. 70%) occurred between the IDF (2005) and the ATP Ⅲ (2005), with a kappa coefficient of 0. 867 (P = 0. 000). Significantly higher morbidity of myocardial infarction (MI) and/or cerebral stroke was found in MS patients regardless which criteria applied. The morbidity of MI and cerebral stroke in MS patients identified by the 4 criteria showed no difference (P = 0. 556). Conclusion ATP Ⅲ (2005) has stricter criteria for MS than the others. The prevalence of MS increases with age. There is no significant difference in the prevalence of MS between the Han and Yi ethnicities. In Sichuan, the CDS(2004) is more applicable than the others.关键词
代谢综合征/诊断标准/一致性Key words
Metabolic syndrome/Diagnostic criteria/Consistency引用本文复制引用
费扬帆,王椿,刘关键,高赟,陈涛,田浩明,冉兴无..不同代谢综合征诊断标准运用于四川地区人群的比较分析[J].四川大学学报（医学版）,2012,43(4):547-552,6.基金项目
国家自然科学基金(No.81170776)资助 （No.81170776）
