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具有内分泌活性的颈动脉体瘤的临床病理特征及其外科治疗

杨家印 曾国军 赵纪春 马玉奎 黄斌 杨轶 冯会芳 要文青

四川大学学报(医学版)2012,Vol.43Issue(4):622-624,3.
四川大学学报(医学版)2012,Vol.43Issue(4):622-624,3.

具有内分泌活性的颈动脉体瘤的临床病理特征及其外科治疗

Clinical and Pathological Characteristics and Surgical Treatment of Carotid Body Tumor with Endocrine Activity

杨家印 1曾国军 1赵纪春 1马玉奎 1黄斌 1杨轶 1冯会芳 2要文青3

作者信息

  • 1. 四川大学华西医院肝脏及血管外科,成都610041
  • 2. 核工业416医院内分泌科,成都610000
  • 3. 四川大学华西医院病理科,成都610041
  • 折叠

摘要

Abstract

Objective To investigate the clinical and pathological characteristics and surgical treatment of carotid body tumor with endocrine activity (CBT). Methods Records of seven CBT patients with endocrine activity (Jan, 1991-Aug, 2011) who underwent surgical excision of tumor were retrospectively reviewed. The operations were performed with the careful peroperative preparation on the control of blood pressure, serum potassium and catecholamine. All the tumors were studied with the methods of HE staining, immunohistochemistry of chromogranin A (CgA) and S-100. Results All the operations were successfully accomplished and the patients recovered quickly. It was confirmed with pathological examination that all the tumors were CBT, coming from paraganglioma. Tumor cells and sertoli cells were found in HE staining, and all were positive of CgA and S-100. All patients were followed up for 12-60 months and no recurrence was found during the follow up. Conclusion CBT with endocrine activity presents with identifiable clinical and pathological characteristics. The recommended treatment is surgical resection, careful perioperative preparation and care is important to avoid the severe complication due to the endocrine activity of tumor.

关键词

颈动脉体瘤/外科切除/内分泌活性

Key words

Carotid body tumor/Resection/Endocrine activity

引用本文复制引用

杨家印,曾国军,赵纪春,马玉奎,黄斌,杨轶,冯会芳,要文青..具有内分泌活性的颈动脉体瘤的临床病理特征及其外科治疗[J].四川大学学报(医学版),2012,43(4):622-624,3.

四川大学学报(医学版)

OA北大核心CSCDCSTPCDMEDLINE

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