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前列腺癌近距离治疗后生化复发预测因素分析

陈健 严维刚 李汉忠 周毅 周智恩

基础医学与临床2012,Vol.32Issue(8):880-883,4.
基础医学与临床2012,Vol.32Issue(8):880-883,4.

前列腺癌近距离治疗后生化复发预测因素分析

Predictors of biochemical outcome of localized prostate cancer after brachytherapy

陈健 1严维刚 1李汉忠 1周毅 1周智恩1

作者信息

  • 1. 中国医学科学院北京协和医学院北京协和医院泌尿外科,北京100730
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摘要

Abstract

Objective To analyze the predictors of biochemical outcome of localized prostate cancer after brachytherapy in conjunction with neoadjuvant hormonal therapy. Methods Clinical and pathological data from 50 patients with localized prostate cancer underwent neoadjuvant hormonal therapy followed by brachytherapy are retrospectively reviewed, including Gleason score, TNM clinical stage, risk level, pre and after neoadjuvant hormonal therapy PSA level PSA1,PSA2,percentage of positive biopsy PPB1 and PPB2. Results TNM clinical stage,risk level,PSAl, PPB1 and PPB2 are significantly associated with biochemical failure, while Gleason score and PSA2 are not so. Conclusions TNM clinical stage,risk level,PSAl, PPB1 and PPB2 can be used as the predictors of biochemical failure of localized prostate cancer after brachytberapy in conjunction with neoadjuvant hormonal therapy.

关键词

近距离治疗/新辅助内分泌治疗/生化复发

Key words

hrachy therapy/neoadjuvant hormonal therapy/biochemical failure

分类

医药卫生

引用本文复制引用

陈健,严维刚,李汉忠,周毅,周智恩..前列腺癌近距离治疗后生化复发预测因素分析[J].基础医学与临床,2012,32(8):880-883,4.

基金项目

中央保健局基金(B2009B091) (B2009B091)

基础医学与临床

OA北大核心CSCDCSTPCD

1001-6325

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