计算机工程2012，Vol.38Issue(13)：48-50,3.DOI:10.3969/j.issn.1000-3428.2012.13.013
基于Hadoop的化合物生物活性分析系统
Compounds Biological Active Analysis System Based on Hadoop
摘要
Abstract
The prediction of biological active compounds, which requires heavy computation in practice, is more and more important in drug discovery and chemical genornics. This paper proposes a Hadoop-based parallelized method for searching and predicting drug-like compounds combining MapReduce model, and the method is realized through Hadoop tool. According to the problems of the inhomogeneity of Hadoop partition algorithm, and computation of fault-tolerant function, the method is improved. Experimental results show that the method provides an effective, scalable and simple way to solve the heavy computation problem, and its average accelerated efficiency achieves 0.91.关键词
生物活性/生物信息学/并行计算/可扩展性/数据库/Hadoop框架Key words
biological activity/ bioinformatics/ parallel computing/ scalability/ database/ Hadoop frame分类
信息技术与安全科学引用本文复制引用
李杰辉,张亮,陈健,南蓬..基于Hadoop的化合物生物活性分析系统[J].计算机工程,2012,38(13):48-50,3.基金项目
国家“863”计划基金资助项目(2009AA02Z308) （2009AA02Z308）
