摘要
Abstract
Objective To explore whether there are differences in terms of clinical features and medical treatments between the young - and middle - aged and elderly patients with depression by a retrospective analysis of 267 adult patients with depression. Methods A retrospective analysis was conducted to review the clinical data of 299 patients who received treatments in our hospital between 2010 and 2011. A total of 267 patients who met the requirements of the study were finally selected and divided into young and middle - aged group (n = 234) and the elderly group (n = 33). Results The two groups showed statistically significant differences in age, educational background and marital status, but no significant statistical differences were found in gender and family history. In terms of life events, there was no statistically significant difference between the two groups (P > 0.05). The incidence rate of somatization disorders was higher in the elderly group than in the young and middle- aged group (P<0.05). The incidence rates of emotional change, suicidal intention and somatization symptoms, particularly suicidal intentions and somatization symptoms, were higher in the elderly group than in the young and middle-aged group (P<0.05, P<0.01, P< 0.05). Two groups showed no statistically significant differences in medical treatments, including the combination of antidepressants and traditional Chinese medicines. Conclusion There are many causes leading to the depression in adults, moreover the percentage of depression resulting from somatic disease could increase along with increase of age. And also a difference in clinical manifestations exists in adult depression patients. Compared with the young and middle-aged patients, the
elderly patients have more emotional changes , suicidal intentions and somatization symptoms . However, dult patients may have no statistically significant differences in choosing antidepressant drugs.关键词
成年人/抑郁症/临床特征/治疗药物/回顾分析Key words
adults/ depression/ clinical features/ therapeutic drugs/ retrospective analysis分类
医药卫生