实用临床医药杂志2012,Vol.16Issue(7):75-77,3.
氯吡格雷对不稳定型心绞痛患者血浆炎症因子及血小板活化因子水平的影响
Influence of clopidogrel on the levels of plasma inflammatory factor and platelet activating factor in patients with unstable angina
摘要
Abstract
Objective To study the influence of clopidogrel on the levels of plasma inflammatory factor (PIF) and platelet - activating factor (PAF) in patients with unstable angina (UA) Methods The selected patients were randomly divided into two groups. The control group received conventional treatment of UA programs, while the treatment group received additional clopidogrel on the basis of conventional methods. The clinical efficacy and adverse events were observed in the two groups. Results The levels of PIF and PAF were significantly decreased after treatment (P< 0.05) in both groups, especially in the treatment group. No obvious adverse events were observed in both groups. Conclusion Clopidogrel can effectively inhibit the inflammation response in the vascular plaque and platelet activation, which is of important significance for the treatment and prevention of UA.关键词
氯吡格雷/不稳定型心绞痛/炎症因子/血小板活化因子Key words
clopidogrel/ unstable angina/ inflammatory factors/ platelet - activating factors分类
医药卫生引用本文复制引用
罗北海..氯吡格雷对不稳定型心绞痛患者血浆炎症因子及血小板活化因子水平的影响[J].实用临床医药杂志,2012,16(7):75-77,3.基金项目
中国高校医学期刊临床专项资金(11220021) (11220021)