实用临床医药杂志2012，Vol.16Issue(7)：80-82,3.
氯沙坦钾对原发性高血压合并高尿酸血症患者血尿酸代谢的影响
Effect of losartan potassium on the metabolism of blood uric acid in essential hypertension patients complicated with hyperuricemia
袁斌斌 1刘向东 1布艾加尔·哈斯木1
作者信息
- 1. 江苏省南京明基医院南京医科大学附属医院心内科,江苏南京,210019
- 折叠
摘要
Abstract
Objective To evaluate the clinical efficacy of losartan potassium in essential hypertension patients complicated with hyperuricemia. Methods Sixty - six essential hypertension patients complicated with hyperuricemia were administered losartan 50 mg/d as an initial dose, and the dose was adjusted according to the level of blood pressure and uric acid. The blood pressure and blood uric acid level were measured one day before and 6 and 12 weeks after the treatment, and adverse effects were observed. Results Both systolic and diastolic blood pressures significantly decreased after the treatment. The serum uric acid level was decreased to various degrees after 6 - week treatment and recovered to normal range after 12 - week treatment. No side reactions were found during the whole treatment. Conclusion Losartan can control blood pressure and decrease uric acid level effectively and safely, thus being contributive to reduce gout attacks. 关键词
原发性高血压/氯沙坦钾/尿酸/高尿酸血症Key words
essential hypertension/losartan potassium/serum uric acid分类
医药卫生引用本文复制引用
袁斌斌,刘向东,布艾加尔·哈斯木..氯沙坦钾对原发性高血压合并高尿酸血症患者血尿酸代谢的影响[J].实用临床医药杂志,2012,16(7):80-82,3.
