摘要
Abstract
Objective To explore the prevalence and its risk factors of microalbuminuria in patients with newly diagnosed type 2 diabetic mellitus (T2DM). Methods A retrospective analysis of 285 patients (173 males, 112 females) with newly diagnosed T2DM was conducted. Based on the ratio of microalbuminuria and creatinine, the patients were divided into diabetic group (DM group) and diabetic plus microalbuminuria group (DpM group). Body mass index (BMI), waist -hip ratio (WHR), blood glucose, blood lipids, blood pressure, insulin resistance index (HOMA- IR) and other factors were observed for group differences and their relation to microalbuminuria/ creatinine ratio. Results Microalbuminuria prevalence of patients with newly diagnosed T2DM was 26.7 %. Prevalence rates in male and female were 24.85 % and 29.46 % respectively. There was no difference in prevalence of microalbuminuria between different genders. The values of BMI, WHR, HbAlc, FPG, SBP, DBP, TC, TG, and HOMA- IR were higher in the DpM group than in the DM group. The correlation analysis showed that the ACR was positively correlated with WHR, BMI, HOMA- IR, SBP, and HbAlc. Logistic regression analysis showed that WHR, SBP and HbAlc were major risk factors affecting the ACR. Conclusion Attention should be paid to the early screening of T2DM patients with urinary albumin. Early strict control of blood sugar and blood pressure, correction of lipid metabolism disorders and reduction of abdominal obesity help to slow down and control the development and progression of diabetic nephropathy.关键词
2型糖尿病/血红蛋白A,糖基化/白蛋白尿Key words
type 2 diabetes mellitus/ hemoglobin A, glycosylated/albuminuria分类
医药卫生
