实用临床医药杂志2012，Vol.16Issue(11)：117-118,126,3.
急性ST段抬高型心肌梗死介入治疗围术期联合盐酸替罗非班和腺苷疗效观察
Therapeutic observation of interventional therapy of tirofiban combined with adenosine for acute ST- segment elevation myocardial infarction in the perioperative period
陈解忠 1丁志坚 1王新 1孙勇1
作者信息
- 1. 南京医科大学附属常州二院心内科,江苏常州,213000
- 折叠
摘要
Abstract
Objective To explore the value of tirofiban combined with adenosine in acute ST- segment elevation myocardial infarction patients who undergo percutaneous coronary intervention (PCI) in the perioperative period. Methods Fifty patients who received PCI surgery between 2010 to 2011 were randomly divided into treatment group ( n = 25) and control group ( n = 25). In the treatment group, adenosine was used before PCI surgery [140 μg/(kg·min)], intravenous injection within 6 min), and tirofiban was used after femoral artery puncture (10 μg/kg intravenous injection within 3 min followed by 0.15 μg/(kg·min) intravenous infusion in 24 hours). Results There were more patients with flow rate over TIMI Ⅲ in the treatment group who received PCI surgery and tirofiban and adenosine. Six months after PCI, left ventricular ejection fraction, cardiac index, stroke volume index significantly increased, and left ventricular end diastolic volume, left ventricular end systolic volume significantly decreased in the treatment group (P<0.05). Conclusion Application of tirofiban combined with adenosine during PCI in patients with acute st - segment elevation myocardial infarction can reduce the occurrence of no - reflow and improve cardiac function.关键词
急性ST段抬高型心肌梗死/PCI术/心功能/替罗非班/腺苷Key words
acute ST - segment elevation myocardial infarction/ percutaneous coronary intervention (PCI) surgery/ no-reflow/ heart function/ tirofiban/ adenosine分类
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陈解忠,丁志坚,王新,孙勇..急性ST段抬高型心肌梗死介入治疗围术期联合盐酸替罗非班和腺苷疗效观察[J].实用临床医药杂志,2012,16(11):117-118,126,3.
